1,2†
1Department of Agrobiotechnology IFA-Tulln, Institute of Environmental Biotechnology, University of Natural Resources and Life Sciences, Vienna, Austria
2Division Polymers & Enzymes, Austrian Centre of Industrial Biotechnology, Graz, Austria
3Institute of Microbiology and Microbial Biotechnology, University of Natural Resources and Life Sciences, Vienna, Austria
4Department of Material Sciences and Process Engineering (MAP), Institute of Physics and Materials Science (IPM), Vienna, Austria
5Department of Microbiology, University of Innsbruck, Innsbruck, Austria
Microorganisms, like bacteria and fungi, are becoming an emerging resource for the development of eco-sustainable plastic degradation and recycling processes. In this study, the rumen content from cattle (
Bos taurus) was investigated regarding synthetic polyester hydrolyzing enzymes based on the fact that the diet of ruminants may contain natural plant polyesters. A screening with model substrates demonstrated h
Germany
Eppendorf
Nordrhein-westfalen
Corbion
Basse-normandie
France
United-states
United-kingdom
Lobnik
Käten
Austria
Steinkellner
This is the story of a series of reductionist studies that started with an attempt to explain what underpins the high-level of aerobic metabolism in mammals (i.e. associated with the evolution of endothermy) and almost forty years later had led to investigations into the role of membrane lipids in determining metabolism. Initial studies showed that the increase in aerobic metabolism in mammals was driven by a combination of increases in mitochondrial volume and membrane densities, organ size and changes in the molecular activity of enzymes. The increase in the capacity to produce energy was matched by an increase in energy use, notably driven by increases in H , Na and K fluxes. In the case of increased Na flux, it was found this was matched by increases in Na -dependent metabolism at the tissue level and increases in enzyme activity at a cellular level but not by an increase in the number of sodium pumps. To maintain Na gradient across cell membranes, increased Na flux is not con
Body-mass
Ctotherm
Ndotherm
Fatty-acid
Ipid
Itochondria
A-flux
Organ-size
Phospholipid
Protein-concentration
Roton