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DW DocFilm July 19, 2019 05:15:00

Only at full speed. Always shining. Luck but always on the move. Played mostly today and in the future. Drive it on t w. The people of the world for information they provide the opinions they want to express t. W. On facebook and twitter up to date and in touch follow us. Canaveral florida july 1990. 3 men set off on one of the greatest adventures in Human History their goal to move. Back the back of the global hundreds of thousands were there to watch. Big. League. The cold war was in full swing and the competition between the u. S. And the soviet Union Extended even to space. On july 20th 1069. 00 astronaut Neil Armstrong became the 1st human to set foot on earth spoke only permanent satellite. Live log file. This event would bring armstrong fame that he had never sought and it would also change his life forever. Strong ....

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From target discovery to clinical drug development with human genetics

The substantial investments in human genetics and genomics made over the past three decades were anticipated to result in many innovative therapies. Here we investigate the extent to which these expectations have been met, excluding cancer treatments. In our search, we identified 40 germline genetic observations that led directly to new targets and subsequently to novel approved therapies for 36 rare and 4 common conditions. The median time between genetic target discovery and drug approval was 25 years. Most of the genetically driven therapies for rare diseases compensate for disease-causing loss-of-function mutations. The therapies approved for common conditions are all inhibitors designed to pharmacologically mimic the natural, disease-protective effects of rare loss-of-function variants. Large biobank-based genetic studies have the power to identify and validate a large number of new drug targets. Genetics can also assist in the clinical development phase of drugs—for example ....

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Pequenas e Médias Empresas vão beneficiar de crédito de nove milhões de contos

Pequenas e Médias Empresas vão beneficiar de crédito de nove milhões de contos
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