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Genetic risk scores 'do not have a place in public health screening'

Researchers said the scoring system led to false positives and ‘performed poorly when predicting if a person would develop common diseases. ....

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Genetic risk scores not useful in predicting disease

Genetic risk scores not useful in predicting disease
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Over the counter genetic tests that claim to predict the risk of illnesses such as heart disease and cancer 'miss nine in ten cases'

University College London researchers found commercially available genetic tests only identified just 11 per cent of individuals who went on to develop disease, such as cancer. ....

United Kingdom , Sam Lambert , Aroon Hingorani , Jasmine Gratton , Michael Inouye , Cambridge University , Institute Of Health Informatics , University College London , Institute Of Cardiovascular Science , Cardiovascular Science , Professor Sir Nicholas Wald , Health Informatics , Professor Michael Inouye , Professor Sam Lambert ,

Genetic risk scores not useful in predicting

<p>The new study, published in <em>BMJ Medicine</em>, looked at 926 polygenic risk scores for 310 diseases. It found that, on average, only 11% of individuals who develop disease are identified, while at the same time 5% of people who do not develop the disease test positive. Unaffected people usually outnumber those affected which results in far more false than true positive predictions.</p>
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Genetic risk scores 'do not have a place in public health screening' | East London and West Essex Guardian Series

Researchers said the scoring system led to false positives and ‘performed poorly’ when predicting if a person would develop common diseases. ....

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