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Microbiome therapy shows potential in graft-versus-host disease

Microbiome therapy shows potential in graft-versus-host disease
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MaaT Pharma Announces Publication of Results from Completed Phase 1/2 ODYSSEE Clinical Trial in Nature Communications


MaaT Pharma Announces Publication of Results from Completed Phase 1/2 ODYSSEE Clinical Trial in Nature Communications
MaaT011 was safe after induction chemotherapy in acute myeloid leukemia patients
MaaT011 formed the basis of the company s full ecosystem therapeutic approach that was continued with product candidatesMaaT013 (in acute graft-vs-host disease) and MaaT033 (in acute myeloid leukemia)
MaaT Pharma announced today that final results from its Phase 1/2 ODYSSEE clinical trial have been published in the journal,
Nature Communications. The data
demonstrated that the company s initial product candidate, MaaT011, an autologous fecal microbiota transfer treatment, was safe and effective in fully restoring the gut microbiota in the 20 per-protocol analyses set of acute myeloid leukemia (AML) patients. In addition, the MaaT011 treatment showed short- and long-term signs of positive clinical outcomes including the reduction of both intestinal inflammatio ....

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