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A tripartite-chromosome E. coli strain allows the chromosome isolation and implantation


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IMAGE: The E. coli chromosome was split into three 1-Mb chromosomes, and the chromosome was used for genome implantation.
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Credit: Rikkyo University
Escherichia coli (
E. coli) genome, consisting of 4.6 million base pairs of a single circular DNA, is too large to manipulate following the extraction and transfer to other bacteria.
In the present study, a group of Rikkyo University researchers led by Assistant Professor Takahito Mukai and Professor Masayuki Su etsugu has succeeded in splitting the E.coli genome into tripartite-genome of 1 million base pairs per genome (split-genome) using the smallest
E. coli genome strain established so far. In addition, they successfully extracted the split-genome from bacteria and installed it in other ....

Takahito Mukai , Masayuki Suetsugu , Nucleic Acids Research On , Rikkyo University , Strategic Basic Research Program , Core Research For Evolutional Science , Assistant Professor Takahito Mukai , Professor Masayuki Su Etsugu , Nucleic Acids Research , Basic Research Program , Core Research , Evolutional Science , Molecular Biology , றிக்கியோ பல்கலைக்கழகம் , மூலோபாய அடிப்படை ஆராய்ச்சி ப்ரோக்ர்யாம் , அடிப்படை ஆராய்ச்சி ப்ரோக்ர்யாம் , கோர் ஆராய்ச்சி ,

A tripartite-chromosome E. coli strain allows chromosome isolation and implantation

A tripartite-chromosome E. coli strain allows chromosome isolation and implantation
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Takahito Mukai , Masayuki Suetsugu , Rikkyo University , Nucleic Acids Research On , Assistant Professor Takahito Mukai , Professor Masayuki Su Etsugu , Nucleic Acids Research , றிக்கியோ பல்கலைக்கழகம் ,