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Combination approach can improve the success rate of cancer treatment

Combination approach can improve the success rate of cancer treatment
A new cancer vaccine could boost the positive effects of existing immunotherapy drugs, improving the success rate of treatments from 20% to 75% of cases, according to a new study by immunologists from the University of Konstanz.
The vaccine, which incorporates a new immunostimulant that is safe for use in humans, was shown to partially eliminate tumors in mice. However, the study further demonstrated that combining the vaccine with an immune checkpoint inhibitor an established immunotherapy drug with a 20% success rate overall for patients can vastly improve the proportion of individuals who respond to treatments, eliminating tumors in 75% of cases in mice. ....

Baden Wüberg , Dennis Horvath , Marcus Groettrup , Julia Koerner , Emily Henderson , Riboxx Pharmaceuticals In Dresden , Nature Communications On , University Of Konstanz , Nature Communications , Professor Marcus Groettrup , Study Senior Author , Riboxx Pharmaceuticals , Advanced Study , Collective Behaviour , Cancer Therapy , Immune Response , டென்னிஸ் ஹார்வத் , ஜூலியா கொஏர்நேற் , எமிலி ஹென்டர்சன் , இயற்கை தகவல்தொடர்புகள் ஆன் , இயற்கை தகவல்தொடர்புகள் , படிப்பு மூத்தவர் நூலாசிரியர் , கூட்டு நடத்தை ,

Parkinson's disease: When molecular guardians need to be protected

Parkinson's disease: When molecular guardians need to be protected
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

Baden Wüberg , Nicola Roverato , Marcus Groettrup , German Research Foundation , Collaborative Research Centre Chemical , University Of Konstanz , Professor Marcus Groettrup , Cell Reports , Collaborative Research Centre , Biological Principles , ஜெர்மன் ஆராய்ச்சி அடித்தளம் , கூட்டு ஆராய்ச்சி மையம் இரசாயன , செல் அறிக்கைகள் , கூட்டு ஆராய்ச்சி மையம் , உயிரியல் ப்ரிந்ஸிபல்ஸ் ,

New vaccination method aims at comprehensive protection against all known influenza mutations

New vaccination method aims at comprehensive protection against all known influenza mutations
One shot, protected forever: This would be a dream come true regarding influenza vaccinations. So far, vaccination against influenza did not provide a lasting protection. The reason: Influenza viruses mutate very fast. Every year, new virus strains emerge against which previous vaccinations provide no or only limited protection. To avoid having to vaccinate against the flu every year, a research network consisting of the University of Konstanz, the University of Tübingen and Technische Universität Dresden is testing an alternative vaccination method. This new method aims at comprehensive protection against all known influenza mutations and thus is a promising candidate for reaching lasting immunity. ....

Baden Wuberg , Oliver Planz , Marcus Groettrup , Technische Universit , Peter Martus , Jacques Rohayem Technische Universit , Emily Henderson , Jacques Rohayem , Klinische Epidemiologie , Professor Peter Martus University Hospital , Interfaculty Institute For Cell Biology , University Hospital Of Tuebingen , Professor Marcus Groettrup University Of Konstanz , University Of Konstanz , Ministry Of Education , Professor Oliver Planz University , Professor Marcus Groettrup , Federal Ministry , Professor Oliver Planz , Professor Peter Martus , University Hospital , Professor Jacques Rohayem , Interfaculty Institute , Cell Biology , Clinical Trial , Electron Microscopy ,

A general influenza vaccine

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IMAGE: Biodegradable microspheres that are produced via spray drying. They contain an influenza virus antigen and an immunostimulating substance. The image was obtained by electron microscopy, enlarged 3,000 times.
Copyright: Dennis.
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Credit: Dennis Horvath, University of Konstanz
One shot, protected forever: This would be a dream come true regarding influenza vaccinations. So far, vaccination against influenza did not provide a lasting protection. The reason: Influenza viruses mutate very fast. Every year, new virus strains emerge against which previous vaccinations provide no or only limited protection. To avoid having to vaccinate against the flu every year, a research network consisting of the University of Konstanz, the University of Tübingen and Technische Universität Dresden is testing an alternative vaccination method. This new method aims at comprehensive protection against all known influenza mutations and thus is a pro ....

Baden Wuberg , Oliver Planz , Dennis Horvath , Marcus Groettrup , Technische Universit , Peter Martus , Jacques Rohayem Technische Universit , Jacques Rohayem , Klinische Epidemiologie , Professor Peter Martus University Hospital , Interfaculty Institute For Cell Biology , University Hospital Of Tuebingen , Professor Marcus Groettrup University Of Konstanz , University Of Konstanz , Ministry Of Education , Professor Oliver Planz University , Professor Marcus Groettrup , Federal Ministry , Professor Oliver Planz , Professor Peter Martus , University Hospital , Professor Jacques Rohayem , Interfaculty Institute , Cell Biology , Health Care , Medicine Health ,