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COVID-19 Australia: Virus experts push for fourth booster shots

Epidemiologists say the window to approve a new Omicron-targeting vaccine before a third wave hits is closing fast and Australia should approve a wider rollout of a fourth booster shot. ....

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The Coalition for Epidemic Preparedness Innovations (CEPI) Partners With Bharat Biotech, and Others to Make a 'Variant-Proof' COVID Vaccine

It will fund the researchers to conduct activities including immunogen design, preclinical studies, and a Phase 1 clinical trial. In this, modified immunogens will be produced in a scalable process with high purity and yield at a low cost.

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Coronavirus Australia: Vaccines will handle 'all viral flavours', early evidence suggests

But the vaccines being produced by Moderna, Pfizer and AstraZeneca all generate much higher levels of immunity than natural infection alone and because of that scientists expect them to still cover variants of the virus that cut the effectiveness of vaccine-induced antibodies.
Three new studies, none of which have yet been peer reviewed, suggest that will be the case.
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Natural infection â and vaccines â generate a very wide variety of antibodies, each designed to attach themselves to a different part of the virus.
Antibodies that stick to COVID-19âs spike â the cellular harpoon SARS-CoV-2 uses to bind to human cells â are key, because they can block the virus from infected cells. ....

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