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Study explores how human ACE2 variants can modify SARS-CoV-2 binding


Study explores how human ACE2 variants can modify SARS-CoV-2 binding
A recent tour-de-force study by researchers from the United Kingdom reveals variants of the human angiotensin-converting enzyme 2 (ACE2) that can improve or decrease binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – including two variants with distinct population distributions showing an enhanced affinity for viral spike glycoprotein. This research paper is currently available on the
bioRxiv preprint server while the article undergoes peer review.
Since the start of the coronavirus disease 2019 (COVID-19) pandemic, caused by the SARS-CoV-2, one of the most pertinent questions was why there is such a diverse array of disease outcomes. More specifically, besides older age and the presence of comorbidities, it was not clear whether a genetic component may also play a role in predisposing individuals to a dire prognosis. ....

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Malaysia's health system needs social market reforms · Rebuilding Malaysia


By Professor Geoffrey Williams
Fundamental reform of resources, management and above all governance will be needed for Malaysia to have a world-class health system after the Covid-19 crisis.
Three things are clear from Malaysia’s battle with Covid-19.
First, Malaysia’s frontliners have a world-class commitment to this fight.
Second, under-resourcing of healthcare has been exposed to public scrutiny and concern.
Third, the relationship between the public and private sectors has fallen short of expectations and the leaders have resorted to public bickering in the midst of a global health crisis.
Malaysia needs and deserves a world-class, universal health system which should provide comprehensive, high-quality treatment, free of charge at the point of need, to everyone who needs it, when they need it. Currently the funding, management and governance of healthcare in Malaysia is not fit-for-purpose in delivering this aim. ....

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Botanix | World First Human Clinical Study Shows Synthetic CBD Formula Eradicates Staphylococcus Aureus


Botanix | World First Human Clinical Study Shows Synthetic CBD Formula Eradicates Staphylococcus Aureus
on February 03 2021 10:13 AM
PHILADELPHIA & SYDNEY (BUSINESS WIRE) $BOT#AMR Clinical stage synthetic cannabinoid company Botanix Pharmaceuticals Limited has today published positive data from a world first human clinical study, examining the safety, tolerability and efficacy of its BTX 1801 antimicrobial product for the eradication of
Staphylococcus Aureus (
Staph, also called
golden staph, is a common bacterium that lives on the skin or in the nose. In most situations it is harmless; however, if it enters the body through a cut in the skin, it can cause a range of mild to severe infections, or even death. As part of this study, Botanix was working to minimise the risk of infection by removing or ....

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