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Ageing impairs critical final egg maturation stage
Appeared in BioNews 1093
Oocytes mature differently in older women, in a process that could contribute to a decrease in fertility, a study from scientists in Barcelona, Spain has shown. 
Scientists found that the activity of genes involved in chromosome segregation increased in oocytes progressively with age, while the activity of genes involved in mitochondrial metabolism decreased. Chromosome segregation is needed for cells to divide and multiply, and for RNA processing, while mitochondrial metabolism is essential for cell survival as mitochondria generate the energy needed for all cellular processes.
Here we show that the final step of oocyte maturation itself might be negatively affected by age, which is critical for reproduction because [the oocyte] provides the material early embryos need to develop normally and survive, Professor Bernhard Payer, co-author of the study, told Science Daily.  ....

Comunidad Autonoma De Cataluna , Melanie Krause , Professor Bernhard Payer , காமுனிடட தன்னாட்சி டி கடலுள் , மெலனி க்ராஸ் ,