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Two repurposed drugs and a blue dye show potential as SARS-CoV-2 entry inhibitors


Two repurposed drugs and a blue dye show potential as SARS-CoV-2 entry inhibitors
A new multidisciplinary study from Australia, published in the open-access journal
mBio, shows that three compounds used to treat cystic fibrosis, dry eye, and a specific medical dye may lead to future strategies for the treatment of coronavirus disease (COVID-19).
The ongoing pandemic of COVID-19, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), represents a health emergency that necessitates the continued use of vaccines, but also the development of new drugs to prevent or treat this disease.
However, the latter seems to be a much more complicated issue. Due to the time and cost constraints pertinent to the development of new medications, a drug repurposing process has been posited as a somewhat reasonable approach for now, which entails using drugs that have already been approved for other treatment purposes. ....

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