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Izokibep shows promise in early phase 2 hidradenitis suppurativa trial

NEW ORLEANS — Izokibep, a novel interleukin-17 inhibitor, has shown dramatic responses in hidradenitis suppurativa treatment in an early phase 2 study, according to a speaker at the American Academy of Dermatology Annual Meeting.“[Hidradenitis suppurativa (HS)] is a horrible, horrible disease with a high disease burden. It’s extremely disruptive to anyone’s personal ....

United States , Kima Papp , Kristen Dowd , Fite Biopharma , Byrebeccal Forand , Sanofi Aventis Genzyme , Evelo Biosciences , Seika Pharma , Eli Lilly , Anacor Pharmaceuticals Inc , Arcutis Inc , American Academy Of Dermatology Annual Meeting , Bristol Myers Squibb , Aralez Pharmaceuticals , Gilead Sciences , Probity Medical Research , Dow Pharmaceuticals Sciences Inc , Bausch Health Valeant , Boehringer Ingelheim , Sun Pharmaceuticals , American Academy , Dermatology Annual Meeting , Can Fite Biopharma , Kyowa Hakko Kirin , Meiji Seika Pharma , Mitsubishi Pharma ,

Izokibep Potentially Clears Hidradenitis Suppurativa Lesions at 12 Weeks

A small molecule IL-17A inhibitor, izokibep has additionally shown efficacy in treating psoriatic arthritis and will now be reviewed in a phase 3 HS trial. ....

United States , Kima Papp , Shao Lee Lin , Hidradenitis Suppurativa , American Academy Of Dermatology , Probity Medical Research In Ontario , Drug Administration , American Academy , New Orleans , Probity Medical Research , Hidradenitis Suppurativa Clinical Response ,

Novel topical complex derived from spinach shows efficacy in atopic dermatitis

A novel investigational compound derived from baby spinach leaves yielded improvements in efficacy with an attractive safety profile in adults with atopic dermatitis, according to a study.
“Atopic dermatitis is a common skin disorder for which there remains an unmet need for topical pharmacotherapies that are safe and effective,” Charles Lynde, MD, of Lynde Dermatology, Probity ....

Charles Lynde , University Of Toronto , Probity Medical Research , Devonian Health Group , Lynde Dermatology ,

New Treatment for Adults with Active Psoriatic Arthritis

AbbVie, a research-based global biopharmaceutical company, announced Health Canada has approved SKYRIZI® (risankizumab), for the treatment of adult ....

Kim Alexander Papp , Tracey Ramsay , Probity Medical Research , Health Canada , Probity Medical , Vice President , General Manager ,

Health Canada Approves the Use of RINVOQ® for the Treatment of Adults and Adolescents with Moderate to Severe Atopic Dermatitis

Authorization is based on the results from three Phase 3 multicenter, randomized, double-blind, placebo-controlled registrational clinical trials evaluating the efficacy and safety or RINVOQ in monotherapy or in combination with topical corticosteroids. 1 RINVOQ demonstrated improvements in skin clearance and itch reduction compared to placebo. Milestone marks the third Health Canada-approved indication for RINVOQ . ....

Kim Alexander Papp , Amanda Cresswell Melville , Tracey Ramsay , Abbvie Company , Eczema Society Of Canada , Abbvie Corporation , Canadian Dermatology Association , Probity Medical Research , K Papp Clinical Research , Health Canada , Health Canada Approved , Clinical Research , Eczema Area , Severity Index , Global Assessment , Atopic Dermatitis , Executive Director , Vice President , General Manager , Allergan Aesthetics ,