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Bonnie Bassler , Scientific Research , Canada Gairdner International Award , Microbiology Society Prize Medal , Princeton Department Of Molecular Biology , Asturias Award , Molecular Biology , Gairdner International Award , Society Prize ,

Princeton researchers find a path toward Hep E treatment by disentangling its knotty structure

The hepatitis E virus protein ORF1 contains a region that scientists have struggled to characterize, making the structure and function of this region the subject of much debate. Now, Princeton scientists show that this region of the protein does not behave as a protease, as has been previously suggested, but instead serves as a molecular scaffold to stabilize the rest of the ORF1 protein. ....

Robert Ledesma , Alexander Ploss , Princeton Department Of Molecular Biology ,

As Highly Pathogenic Bird Flu Spreads in U.S., Should Americans Be Worried?

Avian influenza has been detected in poultry flocks as well as wild birds since January. Experts tell Newsweek what the risk is to humans. ....

United States , New York , United States Department Of Agriculture , Munir Iqbal , Peter Barlow , Centers For Disease , Uk Pirbright Institute , Princeton Department Of Molecular Biology , United States Department , Kalamazoo County , Disease Control , Molecular Biology , Professor Peter Barlow , Applied Sciences , Edinburgh Napier University , Bird Flu Pass From Human , Avian Influenza , Bird Flu ,

Princeton-led studies boost CRISPR gene-editing prospects

A Princeton-led team of researchers from the University, MIT, Harvard, and Editas Medicine developed and applied a new method to understand the activity of cellular genes involved in correcting DNA damage, paving the way for dramatic improvements to genome-editing technologies. These advances are described in a pair of papers that appeared online Oct. 14 and Oct. 20, 2021, in the journal "Cell." ....

David Liu , Caitlin Sedwick , Sameera Khan Fotobuddy , John Doench , Britt Adamson , Jonathan Weissman , Jeff Hussmann , Broad Institute , Genetic Perturbation Program , Princeton University Department Of Molecular Biology , Princeton Department Of Molecular Biology , Princeton University Department , Editas Medicine , Princeton Department ,

Princeton-led studies boost CRISPR gene-editing prospects

The ability to edit the genome by altering the DNA sequence inside a living cell is powerful for research and holds enormous promise for the treatment ....

Caitlin Sedwick , Britt Adamson , Jonathan Weissman , Princeton Department Of Molecular Biology , Princeton University Department Of Molecular Biology , Princeton University Department , Editas Medicine , Princeton Department ,