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Experimental cancer drug with GLP-1 agonist can help control weight, manage glucose levels in diabetes patients GLP-1 analogues, also called incretin mimics, are a rather new class of injectable drugs that are given to patients with type 2 diabetes who can’t control their blood glucose levels with oral medications. Representational image. Pixabay A group of researchers at Dr Reddy’s Institute of Life Sciences, India, have found that an experimental cancer drug called MS-275, when used along with a class of diabetes drugs called Glucagon-like peptide 1 agonists or GLP-1 analogues help control blood glucose levels and weight loss in mice models of diabetes associated with obesity. ....
New drug combination improves blood glucose control and weight loss in mice Scientists have shown that adding an experimental cancer drug to a widely used diabetes treatment improves blood glucose control and weight loss in mice, according to a study published today in eLife. The results pave the way for clinical studies of the new drug combination as a more effective long-term treatment for millions of people with diabetes and obesity. Glucagon-like peptide 1 agonists (GLP-1 analogs) are a relatively new class of drugs that reduce blood sugar levels and lower body weight. They partially function by binding to the glucagon-like peptide 1 receptor on pancreatic beta cells, which leads the cells to produce insulin. But not all patients achieve normalization of blood glucose control with GLP-1 drugs, and very few achieve full reversal of obesity. ....
New drug combination could improve glucose, weight control in diabetes ANI | Updated: Dec 23, 2020 16:56 IST Washington [US], December 23 (ANI): Scientists have shown that adding an experimental cancer drug to a widely used diabetes treatment improves blood glucose control and weight loss in mice, according to a study. The study was published in the journal eLife. The results pave the way for clinical studies of the new drug combination as a more effective long-term treatment for millions of people with diabetes and obesity. Glucagon-like peptide 1 agonists (GLP-1 analogs) are a relatively new class of drugs that reduce blood sugar levels and lower body weight. They partially function by binding to the glucagon-like peptide 1 receptor on pancreatic beta cells, which leads the cells to produce insulin. But not all patients achieve normalisation of blood glucose control with GLP-1 drugs, and very few achieve a full reversal o ....
E-Mail Scientists have shown that adding an experimental cancer drug to a widely used diabetes treatment improves blood glucose control and weight loss in mice, according to a study published today in eLife. The results pave the way for clinical studies of the new drug combination as a more effective long-term treatment for millions of people with diabetes and obesity. Glucagon-like peptide 1 agonists (GLP-1 analogs) are a relatively new class of drugs that reduce blood sugar levels and lower body weight. They partially function by binding to the glucagon-like peptide 1 receptor on pancreatic beta cells, which leads the cells to produce insulin. But not all patients achieve normalisation of blood glucose control with GLP-1 drugs, and very few achieve full reversal of obesity. ....