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Vedolizumab induces remission of post-ileal pouch-anal anastomosis chronic pouchitis

1. In this randomized controlled trial, vedolizumab induced remission in patients with chronic pouchitis after undergoing ileal pouch-anal anastomosis (IPAA) for ulcerative colitis as compared to a placebo. 2. The incidence of overall and severe adverse events was comparable between groups. Evidence Rating Level: 1 (Excellent) Study Rundown: Restorative proctocolectomy with IPAA is routinely performed ....

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