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Low adsorption HPLC columns based on MaxPeak high performance surfaces

In this application note, Waters Corporation addresses the limitations of stainless steel HPLC columns due to corrosion and their negative impact on peak shape and analyte recovery. While alternative materials like titanium and nickel-cobalt alloys offer improved corrosion resistance, they still pose challenges for certain analyses. The interaction between analytes and metal surfaces can lead to poor peak shape, analyte losses, and inaccuracies.  To overcome these issues, chromatographers o ....

Waters Corporation , Application Note , Gc Ms ,

Analysis of cephem antibiotics in serum by LC-MS/MS

Cephem antibiotics like penicillin and carbapenems are a type of β-lactam antibiotic used in oral medicines and injectable solutions. Cephem antibiotics are said to be effective for various illnesses because they have a high safety profile with a low frequency and degree of side effects. In this application note, Shimadzu introduce a simultaneous analysis method for cephem antibiotics in blood plasma by LC-MS/MS using the CLAM-2030, which enables fully-automated pretreatment of biologic ....

Application Note , Gc Ms ,