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Polatuzumab Vedotin Substitution in R-mini-CHOP Does Not Worsen High-Grade Toxicities in DLBCL

Using polatuzumab vedotin instead of vincristine in a reduced-dose regimen of rituximab, cyclophosphamide, doxorubicin, and prednisone was not found to increase grade 3/4 hematologic toxicities, infection risk, or neuropathy in elderly patients with untreated diffuse large B-cell lymphoma. ....

Comprehensive Geriatric , Diffuse Largeb Cell Lymphoma , Eha 2023 , Polatuzumab Vedotin Polivy , R Pola Mini Chp , Phase 3 Polar Bear Trial Nct04332822 ,