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KNTV NBC Nightly News With Lester Holt June 4, 2024 00:41:00

But now hope a new drug in a phase 3 clinical trial has proven effective at preventing the growth of lower grade brain tumors i would call this a game changer. reporter: dr. ingle melinhof says this i the first targeted therapy for this type of brain cancer and nearly half of the patients in the trial still haven t needed chemotherapy and radiation, years later. did you just want to scream this from the roof tops, like we may have something here? yes in their 30s, 40s, early 50s, at the height of their professional and personal lives. reporter: nearly 25,000 people are expected to be diagnosed with a malignant brain or spinal cord tumor in the u.s. this year with nearly 19,000 deaths projected the fda is currently working on approving the treatment for everyone rachel learned about the trial a year after surgery and started taking the drug this year there we go so happy to be there. reporter: it has given her relief and a chance at a normal life. ....

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World 'on cusp of first treatments for Alzheimer's disease' after drug trial

Almost half of those on donanemab had no clinical progression of disease at one year compared to 29% on placebo, a study showed. ....

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Quiz on Clinical Trials

Do you know how long it takes to complete a clinical trial? Here are some interesting questions about clinical trials ....

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CNN CNN This Morning Weekend June 4, 2024 11:37:00

Bleeding. cohen says these types of side effects were mostly mild in the trial. we do know that this has a low ratde of causing macro hemorrhage, a low rate less than 1%. in the phase 3 clinical trial there were seven deaths in the placebo group and six in the drug group. according to investigators though, none of the drugs were said to be due to the drug or aria. the new england journal of i had medicine published an additional death of a patient who had been given blood thinners. it s difficult to say it was the drug when another drug can cause significant bleeding. reporter: they agree while this drug shows promise, it must come with caution. for example, avoiding blood thinners while taking the medication. i will prescribe this drug in ....

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CNN The Lead With Jake Tapper June 4, 2024 22:43:00

Hemorrhage, not necessarily fatal, but a low rate, less than 1%. reporter: in the phase 3 clinical trial, there were seven deaths in the placebo cgroup an six in the drug group. none were considered to be due to lecanemab. the new england journal of medicine recently published details of a death of a patient on the drug that had been given blood thinners. it s pretty hard to say lecanemab caused that when you re giving a drug that could cause significant bleeding. however, the combination gives us pause. reporter: neurologist dr. richard isaacson agrees that while this drug shows promise, it must come with caution. for example, avoiding blood thinners while taking the medication. i will prescribe this drug in the right person at the right dose and in a very carefully monitored way. but this drug is not for everyone. reporter: for jack, the possibility of continuing to live a full life, spending quality time with all four ....

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