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FDA Clears Vericiguat to Treat Heart Failure Following Hospitalization Verquvo is the first soluble guanylate cyclase stimulator drug cleared by FDA to treat heart failure January 25, 2021 The U.S. Food and Drug Administration (FDA) approved Merck s Verquvo (vericiguat). It is the first treatment for chronic heart failure approved specifically for patients following a hospitalization for heart failure or need for outpatient IV diuretics. The drug is supposed to reduce the risk of cardiovascular death and heart failure hospitalization in indicated patients with symptomatic chronic heart failure and ejection fraction less than 45%. Vericiguat is a soluble guanylate cyclase (sGC) stimulator, and is the first drug in this class ro be cleared by the FDA for heart failure. ....
Press release content from Business Wire. The AP news staff was not involved in its creation. Merck Announces U.S. FDA Approval of VERQUVO® (vericiguat) January 20, 2021 GMT KENILWORTH, N.J. (BUSINESS WIRE) Jan 20, 2021 Merck (NYSE:MRK), known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration (FDA) has approved VERQUVO, a soluble guanylate cyclase (sGC) stimulator, to reduce the risk of cardiovascular death and heart failure hospitalization following a hospitalization for heart failure or need for outpatient intravenous (IV) diuretics in adults with symptomatic chronic heart failure and ejection fraction less than 45%. The approval of VERQUVO by the FDA, which is the first treatment for chronic heart failure approved specifically for patients following a hospitalization for heart failure or need for outpatient IV diuretics, is based on the results of the pivotal Phase 3 VICTORIA trial and follows a priority re ....