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Disturbed skin microbiome increases the risk of radiodermatitis in radiotherapy patients, finds study

Disturbed skin microbiome increases the risk of radiodermatitis in radiotherapy patients, finds study
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Avidan Neumann , Claudia Traidl Hoffmann , University Hospital , Technical University Of Munich , University Of Augsburg , Association Of Skin Microbiome Dynamics With Radiodermatitis , Technical University , Helmholtz Munich , Environmental Medicine , Skin Microbiome Dynamics With Radiodermatitis , Patients With Breast Cancer ,

How HER2 Targeted Therapies Fight HER2-Positive Metastatic Breast Cancer

HER2-targeted therapies improve outcomes by shutting down growth signaling to cancer cells, targeted delivery of chemotherapy, or blocking intracellular signaling - all leveraging the HER2 receptor to better control metastatic breast cancer. ....

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Factors Informing Individualized Treatment Decision-Making for HER2-Positive Metastatic Breast Cancer

Sara M. Tolaney, MD, MPH explains that treatment decisions for metastatic breast cancer are based on the current biopsy showing receptor status, but prior biopsies over the full course of disease are considered as well, particularly for HER2 targeted therapies which may work even if HER2 low expression occurred years earlier. ....

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Guideline-Recommended Treatments for HER2-Negative Metastatic Breast Cancer

Treatment for HER2-negative metastatic breast cancer depends on factors like hormone receptor status, with chemo/immunotherapy for PD-L1-positive triple negative disease, PARP inhibitors for BRCA mutations, and antibody-drug conjugates as options after first line therapy. ....

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