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Dyne Therapeutics Announces New Clinical Data from ACHIEVE Trial of DYNE-101 in DM1 and DELIVER Trial of DYNE-251 in DMD Demonstrating Compelling Impact on Key Disease Biomarkers and Improvement in Multiple Functional Endpoints

- In Phase 1/2 ACHIEVE Trial, DYNE-101 Demonstrated Dose Dependent 27% Mean Splicing Correction Across All Patients in the 5.4 mg/kg Cohort at 3 Months - - DYNE-101 Showed Improvement in Myotonia,.

United statesStacy nartkerWildon farwellAmy reillyJohn coxExchange commissionDrug administrationMyotonic dystrophy health indexEuropean medicines agencyDyne therapeutics incDose dependentMean splicing correction across all patientsMuscle strengthTimed function testsReported outcomesMean unadjusted

Dyne Therapeutics Announces New Clinical Data from ACHIEVE

- In Phase 1/2 ACHIEVE Trial, DYNE-101 Demonstrated Dose Dependent 27% Mean Splicing Correction Across All Patients in the 5.4 mg/kg Cohort at 3 Months - .

United statesAmy reillyJohn coxStacy nartkerWildon farwellExchange commissionDyne therapeutics incEuropean medicines agencyDrug administrationMyotonic dystrophy health indexDose dependentMean splicing correction across all patientsMuscle strengthTimed function testsReported outcomesMean unadjusted

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