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Tafenoquine following G6PD screening versus primaquine for the treatment of vivax malaria in Brazil: A cost-effectiveness analysis using a transmission model

Author summary Why was this study done? Radical cure with primaquine or recently approved tafenoquine is required to clear the dormant liver parasites of vivax malaria. While single-dose tafenoquine overcomes the barrier of patient adherence to the current 7-day primaquine treatment, it costs more and requires screening for glucose-6-phosphate dehydrogenase (G6PD) deficiency. While the impact of changing policies to tafenoquine after G6PD screening on transmission has been evaluated, the associated costs and cost-effectiveness will be important considerations for policymakers. What did the researchers find? Using an economic evaluation model coupled with a transmission model, we found that prescribing tafenoquine to vivax malaria patients without G6PD deficiency would be highly likely to be cost-effective in Brazil. Tafenoquine will be particularly cost-effective in settings where patient adherence to the current 7-day treatment is low and when paediatric tafenoquine is available ....

Papua New Guinea , United States , South Korea , Republic Of Korea , Monte Carlo , Jamesg Beeson , Brazilian Unified Health System , National Malaria Control Programme , Ministry Of Health Brazil , Burnet Institute , Technological Development Cnpq , World Health Organisation , Melinda Gates Foundation , National Council For Scientific , National Commission For The Incorporation Of Technologies , Ministry Of Health , National Malaria Prevention , Creative Commons Attribution License , National Council , Technological Development , United States Dollars , South America , While Scenarios , Epidemiological Surveillance Information System , National Commission , Brazilian Unified Health ,

Norsk Hydro Takes $571 Million Hit in Weak Alumina Market

Norsk Hydro Takes $571 Million Hit in Weak Alumina Market
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New South Wales , Hilde Merete Aasheim , Alunorte To Glencore Plc , Glencore Plc , Executive Officer Hilde Merete Aasheim ,

Norsk Hydro: Impairments affect Hydro's fourth quarter results

21.12.2023 - Faced with challenging alumina market conditions and Australian power price insecurity, Norsk Hydro ASA will report total impairment losses of approximately NOK 5.9 billion in its fourth quarter results. Hydro will write down the value of: . ....

New South Wales , Elitsa Boyadzhieva , Hilde Merete Aasheim , Halvor Molland , Aluminium Metal , Norsk Hydro , Abuse Regulation , Securities Trading , Norsk Hydro Unternehmensanleihe 1 , 125 Bis 04 25 , Norsk Hydro Unternehmensanleihe 2 , 00 Bis 04 29 , Orsk Hydro Aktie ,