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Mourning the loss of James Raisbeck, Hutch supporter and aviation leader

Mourning the loss of James Raisbeck, Hutch supporter and aviation leader
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MSK scientists learn how genes and environment conspire in pancreatic cancer development

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Like weeds sprouting from cracks in the pavement, cancer often forms in sites of tissue damage. That damage could be an infection, a physical wound, or some type of inflammation. Common examples include stomach cancer caused by H. pylori infection, Barrett s esophagus caused by acid reflux, and even smoking-induced lung cancer.
Exactly how tissue damage colludes with genetic changes to promote cancer isn t fully understood. Most of what scientists know about cancer concerns advanced stages of the disease. That s especially true for cancers such as pancreatic cancer that are usually diagnosed very late.
Researchers in Scott Lowe s lab at the Sloan Kettering Institute are now trying to zero in on the earliest stages of pancreatic cancer development. ....

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