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Genetic changes in head and neck cancer, immunotherapy resistance identified


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A multi-institutional team of researchers has identified both the genetic abnormalities that drive pre-cancer cells into becoming an invasive type of head and neck cancer and patients who are least likely to respond to immunotherapy.
Through a series of surprises, we followed clues that focused more and more tightly on specific genetic imbalances and their role in the effects of specific immune components in tumor development, said co-principal investigator Webster Cavenee, PhD, Distinguished Professor Emeritus at University of California San Diego School of Medicine.
The genetic abnormalities we identified drive changes in the immune cell composition of the tumors that, in turn, dictates responsiveness to standard of care immune checkpoint inhibitors. ....

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Output push to boost demand for imported recycled metals


Output push to boost demand for imported recycled metals
By ZHONG NAN |
China Daily |
Updated: 2021-01-08 09:41
Employees check aluminum rolls made of recycled material at a reprocessing facility in Zouping, Shandong province. [Photo by Dong Naide/For China Daily]
Copper, aluminum and brass among materials critical to revival of factories
Demand for imported recycled metals, including secondary copper and aluminum, will continue to surge in China, thanks to the country s favorable policies to support the growth of both manufacturing and recycled metals, said officials and business owners.
In October, the government introduced a policy regulating the import of recycled brass, copper and cast aluminum alloys to better manage the purchase of certain recycled metals and supply more reclaimed production goods to factories across the country. ....

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