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Chemoprevention for malaria with monthly intermittent preventive treatment with dihydroartemisinin–piperaquine in pregnant women living with HIV on daily co-trimoxazole in Kenya and Malawi: a randomised, double-blind, placebo-controlled trial

Chemoprevention for malaria with monthly intermittent preventive treatment with dihydroartemisinin–piperaquine in pregnant women living with HIV on daily co-trimoxazole in Kenya and Malawi: a randomised, double-blind, placebo-controlled trial
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Tao chenUnited kingdomNairobi areaPalinji mungoniFredrick omitiKatie daviesMichael asemboIb christian bygbjergTracy seddonAndy stergachisSheila nyarindaBenta kamireBernard owinoJohn chabukaSteve taylorAtusaye ngwira

Effect of monthly intermittent preventive treatment with dihydroartemisinin–piperaquine with and without azithromycin versus monthly sulfadoxine–pyrimethamine on adverse pregnancy outcomes in Africa: a double-blind randomised, partly placebo-controlled trial

Monthly IPTp with dihydroartemisinin–piperaquine did not improve pregnancy outcomes, and the addition of a single course of azithromycin did not enhance the effect of monthly IPTp with dihydroartemisinin–piperaquine. Trials that combine sulfadoxine–pyrimethamine and dihydroartemisinin–piperaquine for IPTp should be considered.

Handeni districtUnited kingdomUttar pradeshHoma bayDar es salaamNairobi areaTamil naduEvelyne delylah ondiekiTao chenAtusaye ngwiraEdwin nyaleAmina farahAndy stergachisKelly byrneJoyce mbwanaPalinji mungoni