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Targeting SORT1 To Unlock The Potential Of PeptideDrug Conjugates in Oncology

Targeting SORT1 To Unlock The Potential Of PeptideDrug Conjugates in Oncology
pharmaceuticalonline.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from pharmaceuticalonline.com Daily Mail and Mail on Sunday newspapers.

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Endometrial Cancer Market to Exhibit Moderate Growth Rate During the Forecast Period (2022-2032), Investigates DelveInsight | Key Companies - Hoffmann-La Roche, GlaxoSmithKline, AstraZeneca, Karyopharm Therapeutics, Evergreen Therapeutics, Merck Sharp & Dohme LLC |

Endometrial Cancer Market to Exhibit Moderate Growth Rate During the Forecast Period (2022-2032), Investigates DelveInsight | Key Companies - Hoffmann-La Roche, GlaxoSmithKline, AstraZeneca, Karyopharm Therapeutics, Evergreen Therapeutics, Merck Sharp & Dohme LLC |
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Gaucher Disease Market Report 2032: Epidemiology Data, Pipeline Therapies, Latest FDA, EMA, PDMA Approvals by DelveInsight | Key Companies - Sanofi, Avro Bio, Freeline Therapeutics, Takeda, Pfizer, Genzyme, Actelion, Prevail Therapeutics |

Gaucher Disease Market Report 2032: Epidemiology Data, Pipeline Therapies, Latest FDA, EMA, PDMA Approvals by DelveInsight | Key Companies - Sanofi, Avro Bio, Freeline Therapeutics, Takeda, Pfizer, Genzyme, Actelion, Prevail Therapeutics |
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Link between driver of ovarian cancer, metabolism opens up new therapeutic strategies

Link between driver of ovarian cancer, metabolism opens up new therapeutic strategies ANI | Updated: Jan 12, 2021 11:45 IST Washington [US], January 12 (ANI): Mutations that inactivate the ARID1A gene in ovarian cancer increase utilisation of the glutamine amino acid making cancer cells dependent on glutamine metabolism, according to a study by The Wistar Institute published online in Nature Cancer. Researchers also showed that pharmacologic inhibition of glutamine metabolism may represent an effective therapeutic strategy for ARID1A-mutant ovarian cancer. Up to 60 per cent of ovarian clear cell carcinomas (OCCC) have been inactivating mutations in the ARID1A tumor suppressor gene. These mutations are known genetic drivers of this type of cancer, which typically does not respond to chemotherapy and carries the worst prognosis among all subtypes of ovarian cancer.

United statesRugang zhangShuai wuZhang labMicroenvironment metastasis programWistar instituteWistar institute cancer centerMetastasis programOvarian clear cell carcinomasOvarian carcinomaOvarian cancerTherapeutic strategiesஒன்றுபட்டது மாநிலங்களில்ஷுை வுஜாங் ஆய்வகம்ஓவாயரியந் புற்றுநோய்