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Candidate found to inhibit malignant melanoma growth: Possible early warning sign for skin cancer

Candidate found to inhibit malignant melanoma growth: Possible early warning sign for skin cancer
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Hisashi Motomura , Naho Fujii , Osaka Metropolitan University Graduate School Of Medicine , Professor Hisashi Motomura , Osaka Metropolitan University Graduate School ,

Candidate found to inhibit malignant melanoma growth

Candidate found to inhibit malignant melanoma growth
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Hisashi Motomura , Naho Fujii , Osaka Metropolitan University Graduate School Of Medicine , Professor Hisashi Motomura , Osaka Metropolitan University Graduate School ,

Candidate found to inhibit malignant melanoma

Cancer-associated fibroblasts (CAFs) are key factors in the tumor microenvironment, which have been implicated in cancer cell progression. It has also been reported that vesicles called exosomes produced by these CAFs play an important role in cancer progression. An Osaka Metropolitan University research group investigated the effect of CAF-derived exosomes on the growth of malignant melanoma cells. They found that CAF-derived exosomes express CD9 and CD63 transmembrane proteins, and that the CD9-positive exosomes may inhibit the growth of malignant melanoma cells. ....

Hisashi Motomura , Naho Fujii , Osaka Metropolitan University Graduate School Of Medicine , Osaka City University , Method Of Research , Osaka Prefecture University , Anticancer Research , Osaka Metropolitan University , Professor Hisashi Motomura , Osaka Metropolitan University Graduate School , Metropolitan University , Osaka Prefecture , Exosomes Derived , Cancer Associated Fibroblasts Might Inhibit , Malignant Melanoma ,