Live Breaking News & Updates on Organoid Derived Bronchioalveolar Model

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Heidelberg/Germany, 11 January 2021 - Development of an in vitro human-derived tissue model for studying virus infection and disease progression in the alveolar cells of the lungs responsible for oxygen and carbon dioxide exchange with the blood might enable the study of possible therapies for acute respiratory distress syndrome (ARDS) triggered by SARS-CoV-2. Researchers in the Netherlands have demonstrated that the SARS-CoV-2 replicates efficiently in their model resembling the human bronchioalveolar system that is thought to play a critical role in progression of infection towards pneumonia and ARDS.
It is already established that in people infected with COVID-19 or some other respiratory viruses, alveolar injury can trigger a cascade of events that leads to ARDS, restricting transport of oxygen into the blood to dangerously low levels. There is also mounting evidence that the epithelium lining the alveoli plays a major role in progression of COVID-19. However, ....

Marion Pg Koopmans , Charlotted Koopman , Martm Lamers , Joep Beumer , Bartl Haagmans , Debby Schipper , Hans Clevers , Mauroj Muraro , Karel Bezstarosti , Hansq Duimel , Timi Breugem , Raimondbg Ravelli , Samra Riesebosch , Peterj Peters , Jeroenaa Demmers , Annaz Mykytyn , Transmission Electron Microscopy , Organoid Derived Bronchioalveolar Model , Human Alveolar Type , Nathalie Groen , டெப்பி ஸ்கிப்பர் , பரவும் முறை எதிர் மின்னணு நுண்ணோக்கி , நத்தலி இடுப்பு ,