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United States , Qingtai Su , Zirong Chen , Ruolan Han , American Association For Cancer Research , Cancer Prevention Research Institute Of Texas , Development For Onconano Medicine , Onconano Medicine Inc , Nano Medicine , American Association , Cancer Research , Annual Meeting , Vice President , Translational Medicine , Tian Zhao , Onconano Medicine , Cancer Prevention Research Institute ,

Study Reveals Compelling Data for a New Nanoparticle-based Immuno-Therapeutic to Treat Cancer


Prolonged activation of innate immune pathways by a polyvalent STING agonist” published in
Nature Biomedical Engineering shows that a pH-sensitive nanoparticle-based drug developed by Dr. Jinming Gao and team at the University of Texas Southwestern Medical Center (UTSW) could boost the body’s innate immune pathways in the treatment of multiple cancers with a unique mechanism of activating the
STimulator of
INterferon
Genes (STING). OncoNano licensed this technology from UTSW for further development as part of the company’s proprietary pH-activated micelle platform, and Dr. Gao, a co-founder of OncoNano, currently also serves as a consultant for the company.
“We are excited about the study published by our colleagues at UTSW demonstrating that the STING activating polymeric micelle can be selectively triggered in the endosomes and enter the cytoplasm of phagocytic cells to achieve robust antitumor immunity,” said Marty Driscoll, CEO at OncoNano Med ....

University Of Texas Southwestern Medical Center , United States , Jinming Gao , Marty Driscoll , Lauren Arnold , Onconano Medicine Inc , Research Institute Of Texas , Onconano Medicine , Nature Biomedical Engineering , Texas Southwestern Medical Center , Nano Medicine , Cancer Prevention , Research Institute , பல்கலைக்கழகம் ஆஃப் டெக்சாஸ் தென்மேற்கு மருத்துவ மையம் , ஒன்றுபட்டது மாநிலங்களில் , தியாகி ட்ரிஸ்கல் , லாரன் அர்னால்ட் , ஆராய்ச்சி நிறுவனம் ஆஃப் டெக்சாஸ் , இயற்கை உயிர் மருத்துவ பொறியியல் , டெக்சாஸ் தென்மேற்கு மருத்துவ மையம் , நானோ மருந்து , புற்றுநோய் ப்ரெவெந்ஶந் , ஆராய்ச்சி நிறுவனம் ,