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Pfizer's and Lilly's JAK inhibitor safety concerns prompt Europe to scrutinize drug class

Europe's drug regulator said it would look at all JAK inhibitors, following recent results of a clinical trial of Pfizer's rheumatoid arthritis drug Xeljanz, which showed that recipients were more likely to experience cardio problems such as heart attack, stroke or death due to cardiovascular disease. ....

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Eli Lilly, Incyte axe Olumiant in lupus amid eczema stalemate at FDA

Lilly and Incyte are pulling the plug on Olumiant in lupus, the companies announced Friday. Likewise, Olumiant’s application in moderate-to-severe atopic dermatitis could be destined for a complete response letter, the partners warned. ....

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Rheumatoid Arthritis Drug Helps Reduce Hospitalized COVID-19 Mortality

Rheumatoid Arthritis Drug Helps Reduce Hospitalized COVID-19 Mortality
precisionvaccinations.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from precisionvaccinations.com Daily Mail and Mail on Sunday newspapers.

United States , Olumiant Baricitinib , E Wesley Ely , Vanderbilt University Medical Center , Eli Lilly , Precision Vaccinations , University Medical Center , Lancet Respiratory Medicine , North America , Emergency Use Authorization , Direct Relief ,

Fierce Pharma Asia—BioNTech's Asia expansions; Takeda's debt plans; AZ-Daiichi ADC's breast cancer data

BioNTech and Fosun Pharma, Takeda, AstraZeneca and Daiichi Sankyo made our news this week. (Google)
BioNTech is expanding in Asia with a planned regional headquarters and mRNA manufacturing facility in Singapore, plus a joint venture with Fosun Pharma focused on its COVID-19 vaccine in China. Takeda believes revenues from its remaining portfolio can help it pay down debt and grow into the future. Daiichi Sankyo and AstraZeneca s anti-TROP2 antibody-drug conjugate reported early tumor shrinkage data. And more.
With cash flow from selling its COVID-19 vaccine, BioNTech aims to become a “global immunotherapy powerhouse.” After setting up new operations in Europe and the U.S., the mRNA specialist is targeting Asia. It will set up a Southeast Asia regional headquarters in Singapore, accompanied by an mRNA manufacturing facility that could eventually boast an estimated annual capacity of several hundred million doses of mRNA shots. ....

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Patent Waiver the New Pandemic Normal & India's Key Role in Emerging Global Consensus

Patent Waiver the New Pandemic Normal & India’s Key Role in Emerging Global Consensus
News18
1 day ago
Oommen C Kurian
© Provided by News18
Patent Waiver the New Pandemic Normal & India’s Key Role in Emerging Global Consensus
Earlier this year, stark inequities of global vaccine distribution, where limited supplies of COVID vaccine doses are mopped up by richer countries had forced the WHO chief to warn that the world was on the brink of a “catastrophic moral failure”. Lack of access to COVID-19 vaccines is now playing out across the world in terms of daily deaths spiralling out of control in relatively poorer countries, while vaccination efforts have resulted in significant reduction of deaths in the richer countries (Graph 1). The upper middle-income countries have also seen daily deaths plateau and start declining, albeit with a time lag, in tandem with global vaccine distribution statistics. There is dawning realisation tha ....

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