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Improved Molecular Understanding of AP/BP MPN Better Informs Management Approaches

Developing an optimal treatment strategy for patients with accelerated- or blast-phase myeloproliferative neoplasms requires consideration of a patient's ability to tolerate intensive induction therapy, their eligibility for allogeneic stem cell transplant. ....

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COMMANDS: Luspatercept Boosts Population With Lower-Risk Myelodysplastic Syndromes Who Are Freed From Blood Transfusions

The study's lead author said patients would experience improved quality of life due to fewer transfusions and fewer trips to the clinic to receive treatment. ....

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One Step Closer to an MPN Cure

Treatments with JAK inhibitors are continuing to make their way into the MPN space, providing symptom relief, but not yet a cure. ....

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Luspatercept Nearly Doubles Likelihood of Transfusion Independence in Lower-Risk MDS

Luspatercept-aamt led to a higher rate of sustained transfusion independence compared with erythropoiesis stimulating agents in patients with ESA-naïve, lower-risk myelodysplastic syndrome. ....

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Bristol Myers data make case for earlier use of bone marrow disease drug

BioPharma ....

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