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Enhanced SARS-CoV-2 neutralization by dimeric IgA

n 111) and contacts ( K and L) The normalized AUC of anti-RBD IgA (K) or IgG (L) ELISA for patients with gastrointestinal (GI) symptoms ( n 32) and without GI symptoms ( n 117) was plotted. The r and P values for the correlations in (C) to (G) were determined by two-tailed Spearman’s correlations. For (H) to (L), horizontal bars indicate median values. Statistical significance was determined using a two-tailed Mann-Whitney U test. P 0.005) and severity of symptoms ( P 0.0001) but not timing of sample collection relative to onset ( P 0.69) or age ( P 0.22) (Fig. 1, C to F). Concentrations of anti-RBD IgA antibodies correlated strongly with anti-RBD IgG concentrations (

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