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Naturally-occurring peptide shows promise as new therapeutic in bone repair

Birmingham researchers have shown that PEPITEM, a naturally-occurring peptide (small protein), holds promise as a new therapeutic for osteoporosis and other disorders that feature bone loss, with distinct advantages over existing drugs.

Helen dunsterHelen mcgettrickAmy naylorJonathan lewisJames edwardsKathryn frostBusiness developmentInstitute of inflammationMusculoskeletal sciencesUniversity of birminghamNuffield department of orthopedicsUniversity of oxfordPeptide inhibitorTrans endothelial migrationCell reports medicineNuffield department

Bone-Enhancing Peptide Shows Promise as Therapeutic for Osteoporosis and MSK Disorders

Bone-Enhancing Peptide Shows Promise as Therapeutic for Osteoporosis and MSK Disorders
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Kathryn frostHelen mcgettrickJames edwardsAmy naylorJonathan lewisUniversity of oxfordMusculoskeletal sciencesUniversity of birminghamNuffield department of orthopedicsInstitute of inflammationPeptide inhibitorTrans endothelial migrationCell reportsNuffield department

Guselkumab Significantly Improves Disease Activity in PsA Over 100 Weeks

Continuous improvement across all MDA domains was demonstrated over the 100-week timeframe, with approximately 70% of patients achieving near remission in swollen joint count, enthesitis, and the Psoriasis Area and Severity Index (PASI).

United kingdomLaurac coatesNuffield department of orthopedicsUniversity of oxfordHealth assessment questionnaireGroup for researchUniversity of oxford laurac coatesMusculoskeletal sciencesNuffield departmentPsoriasis areaSeverity indexHealth assessment questionnaire disability indexPsoriatic arthritis

COVID-19 vaccines found effective in reducing risk of long COVID symptoms

COVID-19 vaccines found effective in reducing risk of long COVID symptoms
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United kingdomMarti catalaDani prieto alhambraAnnika jodickeOxford astrazenecaWorld health organizationUniversity of oxfordNuffield department of orthopedicsNational institute for healthMusculoskeletal sciencesClinical practice research datalinkCare researchClinical practice researchLancet respiratory medicineNuffield departmentNational institute

Custom-made 3D lab models could unlock the secret to soft tissue joint diseases

Custom-made 3D lab models could unlock the secret to soft tissue joint diseases
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Petera johnsonStephanie dakinNuffield department of orthopedicsMusculoskeletal sciencesUniversity of oxfordLancet rheumatologyNuffield department