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New influenza vaccine strategies aim to enhance protection with T-cell responses

A recent review highlights the need for innovative influenza vaccines that combine T-cell and antibody responses to enhance protection across multiple strains and seasons. ....

Nature Reviews Immunology , T Cell , Covid 19 , Immune Response , Public Health ,

Novel vaccine approach targets AML and other blood cancers

Acute myeloid leukemia (AML) is a type of blood cancer that forms in the soft marrow of the bones, typically attacking cells that would otherwise form the key component of the body's immunodefense system, white blood cells. ....

Anna Slezak , Jeffrey Hubbell , University Of Chicago , Hubbell Lab , Uchicago Pritzker School Of Molecular Engineering , University Of Chicago Medicine Comprehensive Cancer Center , Blood Advances , Pritzker School , Molecular Engineering , Eugene Bell Professor , Tissue Engineering , Pritzker Molecular Engineering , Uchicago Medicine Comprehensive Cancer Center , Acute Myeloid Leukemia , Blood Cancer , Immune Response , Immune System , Myeloid Leukemia , Tissue Engineering ,

SynOx Advances $75M Phase 3 Trial for Rare Tumor Treatment

Could SynOx's $75M Phase 3 Trial Be the Next Big Leap in TGCT Treatment?
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United Kingdom , Daiichi Sankyo , Gray Barlow , Merck Kga , Merck Kgaa , Synox Therapeutics , Tenosynovial Giant Cell Tumour , Bioqube Ventures , Abbisko Therapeutics , Bio Developments , Antibody Drug Conjugates , Seriesb Funding Round ,

First UK real-world study shows promise for sacituzumab govitecan in metastatic breast cancer

The real-world safety and efficacy of sacituzumab govitecan (SG) against metastatic triple-negative breast cancer. ....

United Kingdom , Gorodenkoff Shutterstock , Drug Administration , British Journal , Image Credit , Breast Cancer , Antibody Drug Conjugate , Central Nervous System , Nervous System ,

Research reveals potential target for enfortumab vedotin therapy in urothelial carcinoma

Under the leadership of PD Dr. Niklas Klümper, Assistant Physician at the Department of Urology at the University Hospital Bonn (UKB) and Clinician Scientist of the BMBF-funded ACCENT program and PD Dr. Markus Eckstein, senior physician at the Institute of Pathology at the Uniklinikum Erlangen of the Friedrich-Alexander-University Erlangen-Nürnberg (FAU), an interdisciplinary research team has published new findings that indicate which patients with advanced urothelial carcinoma could benefit in particular from the new targeted therapy with the antibody-drug conjugate enfortumab vedotin. ....

Nordrhein Westfalen , Markus Eckstein Uniklinikum Erlangen , Uniklinikum Erlangen , Markus Eckstein , Department Of Urology , University Hospital Bonn , Institute Of Pathology , Hospital Bonn , Assistant Physician , Clinician Scientist , Friedrich Alexander University Erlangen N , Clinical Oncology , Antibody Drug Conjugate ,