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FDA Expands Enzalutamide Approval to Earlier Prostate Cancer

The expanded approval makes enzalutamide the first and only approved androgen receptor signaling inhibitor in the nonmetastatic castration-sensitive prostate cancer setting. ....

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Prostate Cancer Subgroup May Benefit From Intensified Therapy

In a subset of patients with high-risk prostate cancer, the combination of abiraterone acetate plus prednisone (AAP) and apalutamide may improve outcomes when added to salvage radiation therapy. ....

United States , Washington University , Dana Farber Cancer Institute , Tyler Seibert , Astellas Pharma , Paull Nguyen , Jeffm Michalski , Varian Medical Systems , Myovant Sciences , American Society Of Radiation Oncology , Harvard Medical School , Boston Scientific , University Of California San Diego , European Society Of Medical Oncology Congress , Ge Healthcare , Harvard Medical , Clinical Oncology Genitourinary Cancers , Medical Oncology , California San Diego , Medscape Medical News , American Society , Radiation Oncology , Blue Earth Diagnostics , Janssen Oncology , Cortechs Labs , Cancers Symposium ,

Decoding Endometriosis: Recent Research Fosters Hope

Although the disease afflicts at least 1 out of every 10 women, endometriosis remains a conundrum for patients and their physicians. ....

South Australia , Thomas Tapmeier , Elizabeth Flanagan , Kate Lawrenson , Los Angeles , Matthew Siedhoff , Jacques Donnez , Hugh Taylor , Krina Zondervan , Yale University , Sinai Medical Center , Monash University , University Of Oxford , Drug Administration , European Society Of Human Reproduction , Cedars Sinai Medical Center , New Haven , European Society , Human Reproduction , Marie Madeleine Dolmans , Cell Reports Medicine , Science Translational Medicine , Nature Genetics , Gnrh Antagonists , Onadotrophin Releasing Hormone Antagonists , Onadotrophin Releasing Hormone Receptor Blockers ,

Transgender Youth on Hormone Therapy Risk Substantial Bone Loss

It appears that bone health deserves attention when adolescents are placed on gender-affirming hormone therapy. ....

United States , J Clin Endocrinol , Natalie Nokoff , Michelea Oconnell , World Professional Association Of Transgender Health , Endocrine Society , University Of Colorado School Medicine , Endocrine Society Annual Meeting , Department Of Endocrinology , Colorado School , Royal Children , World Professional Association , Transgender Health , Correlation Between Duration , Transgender Youth , Weight Bearing Exercise , Social Determinants Of Health , Social Issues , Bone Density , Gnrh Agonists , Gonadotropin Releasing Hormone Agonists , Nrh A , Lhrh Agonists , Uteinizing Hormone Releasing Agonists , Adolescent Medicine , Bone Densitometry ,

Long-term Safety of GnRHa Affirmed in Premenopausal Women Undergoing Chemo for Breast Cancer

In premenopausal women with early breast cancer, use of a gonadotropin-releasing hormone agonist during chemotherapy did not increase the risk of cancer recurrence for up to 12 years, according to the PROMISE-GIM6 trial. ....

New York , United States , Columbia University , Neil Vasan , N Lynn Henry , University Of Genova , Reuters Health , University Of Michigan Rogel Cancer Center , Journal Of The National Cancer Institute , Columbia University Medical Center , National Cancer Institute , Lucia Del Mastro , Del Mastro , Disease Lead , Breast Oncology , Michigan Rogel Cancer Center , Ann Arbor , Herbert Irving Comprehensive Cancer Center , New York City , Katherine Crew , Breast Cancer , Alignant Breast Neoplasm , Breast Carcinoma , Alignant Neoplasia , Alignant Neoplasm , Mammary Gland ,