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Breakthrough in gene editing: Enhanced virus-like particles promise new era in genetic disease treatment

Researchers developed an advanced prime editor-engineered virus-like particle (PE-eVLP) system, significantly enhancing gene editing efficiency in human cells and showing potential for treating genetic diseases. ....

Andrii Yalanskyi , Nature Biotechnology , Gesicle Producer , Future Directions , N Vivo , Ucleic Acid ,

UVA discoveries highlight the different roles of blood vessels in solid tumors

Two new discoveries from the Dudley lab at UVA Cancer Center highlight the different roles of blood vessels in solid tumors – and the findings could help prevent breast cancer from spreading and enhance the effectiveness of one of the most important new cancer treatments in many years. ....

Andrewc Dudley , Lily Ramsey , Dae Joong Kim , Cancer Center , Jamie Null , Virginia School , Blood Vessels , Breast Cancer , Immune System , Lymph Nodes ,

Study reveals the molecular mechanisms of dynamic activation of DNMT1 by H3Ub2

This study is led by Dr. Na Yang (State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Key Laboratory of Medical Data Analysis and Statistical Research of Tianjin, Nankai University), and Dr. Bing Zhu (National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Science). ....

Jixue Sun , Emily Henderson , Institute Of Biophysics , Statistical Research Of Tianjin , Bing Zhu National Laboratory Of Biomacromolecules , Key Laboratory Of Medical Data Analysis , Lab Diagnostics Automation , Chinese Academy Of Science , Lab Diagnostics Automation Industry , Nankai University , Community Cluster , College Of Pharmacy , State Key Laboratory , Medicinal Chemical Biology , Key Laboratory , Medical Data Analysis , Statistical Research , Bing Zhu , National Laboratory , Chinese Academy , Automation Industry Focus , Principal Component ,