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Facilitating the Transition to Continuous Bioprocessing Operations


Facilitating the Transition to Continuous Bioprocessing Operations
Pharmaceutical manufacturing equipment
Despite the promise of continuous processing taking over more of drug manufacturing, some obstacles must be overcome. Ash Kumar, a pharmaceutical engineer at Ghent University in Belgium and his colleagues recently asked: Why is batch processing still dominating the biologics landscape?
The opinion of these researchers is that wider adoption will depend on a list of technical, management, and regulatory improvements, including the “application of detailed modeling and expert systems to support the development and regulatory requirements.”
Other experts agree. For example, Nima Yazdanpanah, principal at Procegence, a modeling and simulation service provider, calls modeling and simulation “crucial” in the transition to continuous processing. In particular, he points out that modeling will be needed to design new equipment and processes that can run in a c ....

Nima Yazdanpanah , Ghent University , கெஂட் பல்கலைக்கழகம் ,