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An unexpected doorway into the ear opens new possibilities for hearing restoration

An unexpected doorway into the ear opens new possibilities for hearing restoration
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Jeffery Holt , Barbara Canlon , Niklas Edvall , Evangelia Tserga , Christopher Cederroth , Leo Miyakoshi , Corstiaen Versteegh , Ryszard Stefan , Yuki Mori , Peter Bork , Barbara Mathiesen , Maiken Nedergaard , Kjeld Mollgard , Natalie Hauglund , Karolinska Institute , Novo Nordisk Foundation , Simons Foundation , Kimberly Barber Fund , Tysta Skolan Foundation , European Union Horizon , University Of Copenhagen , Alice Wallenberg Foundation , Laboratory Of Experimental Audiology , National Institute Of Neurological Disorders , Lundbeck Foundation , Human Frontier Science Program ,

Novel method to deliver drugs into inner ear restores hearing in deaf mice

An international team of researchers has developed a new method to deliver drugs into the inner ear. The discovery was possible by harnessing the natural flow of fluids in the brain and employing a little understood backdoor into the cochlea. ....

Jeffery Holt , Niklas Edvall , Kjeld Mollgard , Megan Craig , Barbara Mathiesen , Maiken Nedergaard , Yuki Mori , Peter Bork , Evangelia Tserga , Natalie Hauglund , Ryszard Stefan , Leo Miyakoshi , Christopher Cederroth , Corstiaen Versteegh , Barbara Canlon , National Institute Of Neurological Disorders , Novo Nordisk Foundation , European Union Horizon , Laboratory Of Experimental Audiology , Innovation Programme , Harvard University , Foundation Pour Laudition , Kimberly Barber Fund , Lundbeck Foundation , University Of Copenhagen , Simons Foundation ,

An unexpected doorway into the ear opens new

Researchers have developed a new method to deliver drugs into the inner ear. The discovery was possible by harnessing the natural flow of fluids in the brain and employing a little understood backdoor into the cochlea. When combined to deliver a gene therapy that repairs inner ear hair cells, the researchers were able to restore hearing in deaf mice. ....

Natalie Hauglund , Ryszard Stefan , Evangelia Tserga , Leo Miyakoshi , Christopher Cederroth , Corstiaen Versteegh , Barbara Canlon , Jeffery Holt , Niklas Edvall , Kjeld Mollgard , Barbara Mathiesen , Maiken Nedergaard , Yuki Mori , Peter Bork , Innovation Programme , European Union Horizon , Novo Nordisk Foundation , National Institute Of Neurological Disorders , University Of Copenhagen , Lundbeck Foundation , Kimberly Barber Fund , Foundation Pour Laudition , Harvard University , Human Frontier Science Program , Sheldong Adelson Medical Research Foundation , Simons Foundation ,