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Archaeal enzyme that produces membrane lipids is spectacularly promiscuous


University of Groningen
Cells of all life forms are surrounded by a membrane that is made of phospholipids. One of these are the cardiolipins, which form a separate class due to their unique structure. When studying the enzyme that is responsible for producing cardiolipins in archaea (single-cell organisms that constitute a separate domain of life), biochemists at the University of Groningen made a surprising discovery. A single archaeal enzyme can produce a spectacular range of natural and non-natural cardiolipins, as well as other phospholipids. The results, which show potential for biotechnological applications, were published in the Journal of Biological Chemistry. ....

Adriaanj Minnaard , Nielshj Wolbert , Marten Exterkate , Ruben Lh Andringa , Arnoldjm Driessen , University Of Groningen , Biological Chemistry , பல்கலைக்கழகம் ஆஃப் க்ராநிகந் , உயிரியல் வேதியியல் ,