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The School was informed of immoral conduct that occured between a nun and a female student The Hogar de la Madre Order has been asked to leave campus after a report was given the school by their . ....
Synthetic Oligonucleotides: Regulatory, Analytical & Manufacturing Considerations By Maura Kibbey, Ph.D., and Nick Healy, U.S. Pharmacopeia (USP) After decades of investment, research, and development, the therapeutic value of oligonucleotides has started to materialize. Dozens of developers now have dedicated pipelines for diverse indications such as oncology, central nervous system diseases, cardiometabolic disorders, liver diseases, and viral infections, including COVID-19. A search for “oligonucleotide” on ClinicalTrials.gov returned more than 50 active studies. Advances in analytical methods are helping to support these pipelines. Across the development and release landscapes, methods continue to refine, streamline, and support the development of oligonucleotides from new applications of nuclear magnetic resonance (NMR) spectroscopy that are pushing the boundaries of what can be accomplished in development, to innovative platform approaches for specification a ....