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Value of intravenous thrombolysis in endovascular treatment for large-vessel anterior circulation stroke: individual participant data meta-analysis of six randomised trials

Value of intravenous thrombolysis in endovascular treatment for large-vessel anterior circulation stroke: individual participant data meta-analysis of six randomised trials
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United statesEuropean stroke organisationEuropean society of cardiologyAmerican heart association strokeEuropean society for minimally invasive neurological therapyDevelopment of the instrumentStroke organisationEuropean societyMinimally invasive neurological therapyNeurointerv surgAmerican heartAmerican strokeSystematic evaluationPatients treatedNeurothrombectomy devicesAcute ischemic stroke

Endovascular treatment versus no endovascular treatment after 6–24 h in patients with ischaemic stroke and collateral flow on CT angiography (MR CLEAN-LATE) in the Netherlands: a multicentre, open-label, blinded-endpoint, randomised, controlled, phase 3 trial

In this study, endovascular treatment was efficacious and safe for patients with ischaemic stroke caused by an anterior circulation large-vessel occlusion who presented 6–24 h from onset or last seen well, and who were selected on the basis of the presence of collateral flow on CTA. Selection of patients for endovascular treatment in the late window could be primarily based on the presence of collateral flow.

United statesRio grande do sulNederlandse verenigingStroke alliance for europeEuropean stroke organisationAmerican heart association strokeEuropean cooperative acute stroke studyEuropean society for minimally invasive neurological therapyStroke organisationEuropean societyMinimally invasive neurological therapyStroke allianceAmerican heartAmerican strokeEnglj medNeurointerv surg

Calling for benefit–risk evaluations of COVID-19 control measures

Calling for benefit–risk evaluations of COVID-19 control measures
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United statesUnited kingdomElsevier ltdNeurointerv surgஒன்றுபட்டது மாநிலங்களில்ஒன்றுபட்டது கிஂக்டம்