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Anakinra by Swedish Orphan Biovitrum for Hospital Acquired Pneumonia (HAP): Likelihood of Approval

Anakinra is under clinical development by Swedish Orphan Biovitrum and currently in Phase II for Hospital Acquired Pneumonia (HAP).

United statesBiovitrum sobiAnakinra kineretGlobaldata pharmaceutical intelligence centerSwedish orphan biovitrumHospital acquired pneumoniaPhase transition success rate modelRheumatoid arthritisCryopyrin associated periodic syndromesNeonatal onset multisystem inflammatory diseaseChronic infantile neurologicalArticular syndromeMuckle wells syndromeFamilial cold autoinflammatory syndromeKawasaki diseaseStill disease

Zydus granted Orphan Drug Designation by the USFDA for ZYIL1 in treatment of patients with Cryopyrin Associated Periodic Syndrome

Zydus Lifesciences Ltd today announced that the United States Food and Drug Administration has granted Orphan Drug Designation to ZYIL1, for treatment of patients with Cryopyrin Associated Periodic Syndrome.

United statesPankajr patelZydus lifesciences ltdClinical pharmacology in drug developmentZydus lifesciencesOffice of orphan drug productsDrug administrationCadila healthcare ltdOrphan drug designationCryopyrin associated periodicUnited states foodOrphan drug designationCryopyrin associated periodic syndromeOrphan drug productsClinical pharmacologyDrug development

U S Food and Drug Administration Issues Emergency Use Authorization for KINERET® (anakinra) for the Treatment of COVID-19-Related Pneumonia

Early treatment with KINERET reduced disease progression by 64 percent in hospitalized COVID-19 patientsi WALTHAM, Mass., Nov. 10, 2022 Sobi North America, the North American affiliate of. | November 10, 2022

United statesJohn yeeHellenic institute for the study of sepsisWorld health organizationDrug administrationGlobenewswire incNorth americaNorth americanCoronavirus diseaseNature medicineChief medical officerCosmetic actFor sobiGuided anakinra treatmentSevere respiratory failureHealth organization

Zydus achieves positive Proof-of-Concept in its Phase 2 clinical study of ZYIL1

CAPS is an orphan illness that is caused by NLRP3 activating mutations and is a rare, life-long auto-inflammatory disorder.

Zydus lifesciencesCadila healthcare ltdZydus lifesciences limitedNeonatal onset multisystem inflammatory diseaseCryopyrin associated periodic syndromesSerum amyloidSerious adverse events

Zydus to begin Phase II (a) clinical trial of ZYIL1, a novel oral NLRP3 inflammasome inhibitor

Zydus to begin Phase II (a) clinical trial of ZYIL1, a novel oral NLRP3 inflammasome inhibitor
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Pankajr patelCadila healthcare ltdCadila healthcareTime zoneCryopyrin associated periodic syndromeAssociated periodic syndromeNeonatal onset multisystem inflammatory diseaseCryopyrin associated periodic syndromesInflammatory bowel diseaseMultiple sclerosisAcute respiratory distress syndromeCadila healthcare limited