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Integrating polygenic risk scores in the prediction of type 2 diabetes risk and subtypes in British Pakistanis and Bangladeshis: A population-based cohort study

Sam Hodgson and colleagues investigate whether the common genetic differences associated with type 2 diabetes in people of European ancestry can be transferred to people of British Pakistani and Bangladeshi ancestry, integrating a novel polygenic risk score with an established clinical risk score. ....

United Kingdom , City Of , Hilaryc Martin , Neneh Sallah , Karoline Kuchenbaecker , Rohini Mathur , Williamg Newman , John Wright , Sam Hodgson , Qin Huang , Richardc Trembath , Chrisj Griffiths , King College London , University College London , Faculty Of Life Sciences , London School Of Medicine , British Heart Foundation Research Accelerator , Affiliation Blizard Institute , Affiliation Wolfson Institute Of Population Health , Genetics Institute , School Of Biological Sciences , Affiliation London School Of Hygiene Tropical Medicine , Affiliation Primary Care Research Centre , Affiliations Manchester Centre For Genomic Medicine , Queen Mary University Of London , Genomic Sciences ,