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Unintended impact of COVID-19 pandemic on the rate of catheter related nosocomial infections and incidence of multiple drug resistance pathogens in three intensive care units not allocated to COVID-19 patients in a large teaching hospital | BMC Infectious Diseases

The prevalence of resistant hospital infections in the intensive care unit (ICU) increases mortality and antibiotic resistance. COVID-19 pandemic may have unintended impact on nosocomial infections (NI) and the prevalence of resistant microorganism. The present non-interventional study was performed by a pre and a post survey each lasting 8 months before (March–October 2019) and after (March–October 2020) the onset of COVID-19 pandemic in three ICU’s, not allocated to COVID-19 patients, in Nemazee Hospital, Shiraz, Iran. The rates of the following nosocomial infections were compared at pre- and post-pandemic period: ventilator associated pneumonia (VAP), central line associated blood stream infection (CLABSI), catheter-associated urinary tract infections (CAUTI) and incidence of multiple drug resistance (MDR) pathogens. Pre-pandemic and pandemic incidence of VAP was 23.5 and 17.2 cases per 1000 device-days, respectively; an absolute decrease of 27%. The main reason fo ....

United States , Centers For Disease , International Nosocomial Infection Control Consortium , Zealand Intensive Care Society , Shiraz University Of Medical Sciences , Shiraz University Medical Science , Shiraz Nemazee , Shiraz University , Disease Control , Iran Intensive Care Registry , New Zealand Intensive Care Society , Infection Control Unit , College Station , Nemazee Hospital ,

Frontiers | An Update on Protective Effectiveness of Immune Responses After Recovery From COVID-19

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibits variable immunity responses among hosts based on symptom severity. Whether immunity in recovered individuals is effective for avoiding reinfection is poorly understood. Determination of immune memory status against SARS-CoV-2 helps identify reinfection risk and vaccine efficacy. Hence, after recovery from COVID-19, evaluation of protective effectiveness and durable immunity of prior disease could be significant. Recent reports described the dynamics of SARS-CoV-2 -specific humoral and cellular responses for more than six months in convalescent SARS-CoV-2 individuals. Given the current evidence, NK cell subpopulations, especially the memory-like NK cell subset, indicate a significant role in determining COVID-19 severity. Still, the information on the long-term NK cell immunity conferred by SARS-CoV-2 infection is scant. The evidence from vaccine clinical trials and observational studies indicates that hybrid natural/ ....

Eastern Cape , South Africa , Western Cape , Saudi Arabia , United Kingdom , South Korea , Free State , Yunbao Pan , Paige Lawrence , Zhengm Tim , Cohen Tervaert , Cullym Exosome , Jernbom Falk , Nasrin Shokrpour , Shiraz University Of Medical Science , Health Sci , Terminal Differentiation Of Plasma Cells In Health , Shiraz University Of Medical Sciences , Development Of Clinical Research Nemazee Hospital , S Specific Igg , Natural Immunity , Vaccine Immunity , Shiraz University , Medical Science , Medical Sciences , Clinical Research ,

Zinc for Colds: In 1960s, This Bihar-Born Doctor First Revealed Its Benefits to Humans

Dr Ananda Prasad from Bihar pioneered the study of zinc deficiency and published over 300 papers and 15 books. ....

New York , United States , Eteläuomen Läi , Bihar Buxar , University Of Helsinki , Wayne State University In Detroit , Patna Medical College , Department Of Biochemistry , Medicine Of Vanderbilt University , University Of Michigan , National Academy Of Sciences , New York Times , University Of Minnesota , Department Of Medicine , Division Of Haematology , Nemazee Hospital , American Journal , Harri Hemila , Ananda Prasad , Mahidol Award , Vanderbilt University , Middle East , Wayne State University , National Academy , Trace Elements ,