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MRSA skin infections are often treated with intravenous injection of antibiotics, which can cause significant side effects and promote the development of resistant bacterial strains. To solve these problems, researchers at Karolinska Institutet in Sweden are developing a microneedle patch that delivers antibiotics directly into the affected skin area. New results published in
Advanced Materials Technologies show that the microneedle patch effectively reduces MRSA bacteria in the skin.
MRSA (methicillin resistant Staphylococcus aureus) skin infections are potentially lethal, especially in patients with compromised immune systems. Vancomycin is one of the main treatments and is given as an intravenous injection. The reason the antibiotic is not given locally is because of its low ability to penetrate the skin. It is not given orally either because of poor absorption through the gut. The problem with systemic administration is that it often results in significan ....

Karolinska Institutet , Liv Eidsmo , Keira Melican , Jill Ziesmer , Georgiosa Sotiriou , Nele Johanna Hempel , Poojabahen Tajpara , Marcus Ehrstr , Georgios Sotiriou , Swedish Research Council , Department Of Microbiology , European Research Council , World Economic Forum , Swedish Foundation For Strategic Research , Advanced Materials Technologies , Cell Biology , Faculty Board , Swedish Foundation , Loaded Microneedle Arrays , Methicillin Resistant Staphylococcus Aureus Skin , கேர மெலிகன் , ஸ்விட்ச் ஆராய்ச்சி சபை , துறை ஆஃப் நுண்ணுயிரியல் , ஐரோப்பிய ஆராய்ச்சி சபை , உலகம் பொருளாதார மன்றம் , ஸ்விட்ச் அடித்தளம் க்கு மூலோபாய ஆராய்ச்சி ,