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FDA Denies Approval of Roluperidone for Negative Symptoms of Schizophrenia

Roluperidone is an investigational drug intended to specifically block the serotonin receptor subtype, 5-HT2A, as well as the sigma2 and adrenergic-α1A receptors. ....

Remy Luthringer , Minerva Neurosciences , Drug Administration , Complete Response Letter , New Drug Application , Negative Syndrome Scale , Negative Symptoms Factor Score , Executive Chairman ,