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England's young cystic fibrosis patients face new treatment worry

Young English sufferers of cystic fibrosis (CF) face new uncertainty after regulators published proposals which, if enacted, would restrict access to potentially life-changing treatments on cost grounds. The National Institute for Health and Care Excellence (NICE) on Friday published draft guidance that it would not recommend three treatments known as modulator therapies, manufactured by Vertex Pharmaceuticals for use on new patients. The draft guidance, open for consultation until Nov. 24, would not affect those who already take Kaftrio or Symkevi, which are currently recommended for patients aged 6 and over, or Orkambi, which can be used at age 1 and over. ....

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Some nice rainfall amounts possible locally over the weekend

(Undated) The National Weather Service says that chances for rain will increase late Friday and then remain elevated through the weekend as periods of rain with embedded thunderstorms are expected. Cooler ....

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NICE Recommends Ruxolitinib for Hydroxycaramide/Hydroxyurea Resistant or Intolerant Polycythemia Vera

The National Institute for Health and Care Excellence has published its Final Draft Guidance recommending the use of ruxolitinib as treatment for eligible patients in England and Wales with polycythemia vera that is resistant or intolerant to hydroxycarbamide/hydroxyurea. ....

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Lilly's diabetes drug gains backing of UK watchdog -Bloomberg News

Mounjaro is expected to become a blockbuster treatment if it is also approved to treat obesity and a U.S. decision on its use for weight loss is expected later this year. Bloomberg News quoted Helen Knight, director of medicines evaluation at the National Institute for Health and Care Excellence (NICE) as saying that Mounjaro has the potential to "provide an effective and good value treatment option" for people with type 2 diabetes that isn't well controlled by other drugs. ....

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Lilly's diabetes drug Mounjaro approved by UK watchdog

The National Institute for Health and Care Excellence (NICE) said in draft final guidance that it estimates some 180,000 people could benefit from the new treatment. Lilly's share price has surged, with investors betting that an approval will make it a blockbuster drug. Final guidance from NICE is scheduled to be published on Oct. 11 after which the drug will be made available in the UK's National Health Service (NHS) within 90 days. ....

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