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Germs in borehole water can cause peptic ulcer, stomach cancer — Oke

Dr Temitope Oke, a gastroenterologist at University College Hospital (UCH), Ibadan, in this interview by SADE OGUNTOLA, reveals that some cases of stomach ....

Port Harcourt , World Health Organisation , University College Hospital , National Health Insurance System ,

Risk-reducing decisions regarding germline BRCA pathogenic variant: focusing on the timing of genetic testing and RRSO

Background In Japan, the public insurance policy was revised in 2020 to cover hereditary breast and ovarian cancer (HBOC), including genetic testing and surveillance, for patients with breast cancer (BC). Consequently, the demand for risk-reducing salpingo-oophorectomy (RRSO) has increased. This study aimed to clarify the changes in the demand and timing of genetic testing and RRSO associated with public insurance coverage for HBOC in Japan.

Methods This retrospective analysis included 350 women with germline BRCA (g BRCA ) pathogenic variants (PVs) who had visited gynaecologists; they received g BRCA genetic testing at 45.1±10.6 (20–74) years. The use of medical testing and preventive treatment was compared between the preinsurance and postinsurance groups using Mann-Whitney U and Fisher’s exact tests.

Results The findings indicate that RRSO rates doubled from 31.4% to 62.6% among patients with g BRCA -PV. The implementation rate was 32.4% among unaffected carrier ....

South Korea , United Kingdom , Eteläuomen Läi , United States , Angelina Jolie , Preventive Services Task , National Health Insurance System , Japanese Organization Of Hereditary Breast , National Comprehensive Cancer Network , Cancer Institute Hospital , Japanese Foundation For Cancer Research , Japanese Organization , Hereditary Breast , Ovarian Cancer , Gene Etude Prospective Sein Ovaire , Preventive Services Task Force , Japanese Foundation , Cancer Research ,

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