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May 04, 2021 Photo by Robert Lisak Nancy H. Ruddle, PhD, John Rodman Paul Professor Emerita at the Yale School of Public Health and the Yale School of Medicine has been selected as the 2021 recipient of the Connecticut Medal of Science. Ruddle is a pioneering immunologist who discovered lymphotoxin, an immune signaling molecule or cytokine and demonstrated its roles and mechanisms in cytotoxicity, autoimmune diseases such as multiple sclerosis and Type 1 diabetes, and in lymph node development. Her work was fundamental to the understanding of tertiary lymphoid organs, accumulations of lymphoid cells that are damaging in autoimmunity but can be key to defense against microorganisms and tumors. ....