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Researchers Gain Insight into Rare Autoimmune Condition

Researchers Gain Insight into Rare Autoimmune Condition
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United States , Nan Yan , Christian Wysocki , Children Medical Center Dallas , Department Of Immunology , Columbia University , Primary Immunodeficiency Clinic , Medical Center Dallas , Science Immunology ,

Researchers identify immune protein linked to rare neurodegenerative disease


Researchers identify immune protein linked to rare neurodegenerative disease
UT Southwestern researchers have identified an immune protein tied to the rare neurodegenerative condition known as Niemann-Pick disease type C. The finding, made in mouse models and published online in
Nature, could offer a powerful new therapeutic target for Niemann-Pick disease type C, a condition that was identified more than a century ago but still lacks effective treatments.
Niemann-Pick disease has never been considered an immune disorder. These findings put it in a whole new light.
Nan Yan, Ph.D., study leader, associate professor of immunology and microbiology
Niemann-Pick disease type C, which affects about 1 in every 150,000 people worldwide, has long been considered a disease of cholesterol metabolism and distribution, a topic well-studied at UT Southwestern, where faculty members Michael Brown, M.D., and Joseph Goldstein, M.D., won the Nobel Prize in 1985 for their disco ....

Nan Yan , Michael Brown , Joseph Goldstein , Emily Henderson , Nobel Prize , நான் யான் , மைக்கேல் பழுப்பு , ஜோசப் கோல்ட்ஸ்டைன் , எமிலி ஹென்டர்சன் , நோபல் ப்ரைஸ் ,