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Simplified process shines light on new catalyst opportunities

Simplified process shines light on new catalyst opportunities
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Tsuyoshi Mita , Wataru Kanna , Yu Harabuchi , Hiroki Hayashi , Satoshi Maeda , Hitomi Katsuyama , Hideaki Takano , Scientific Research , Nature Communications , Transformative Research Areasa Organic Synthesis , Technology Agency Exploratory Research For Advanced , Fugaku Trust For Medical Research , Hokkaido University , Naito Foundation , Challenging Research Exploratory , Uehara Memorial Foundation , Institute For Chemical Reaction Design , Chemical Reaction Design , Top Row , Bottom Row , Photo Credit , Japan Science , Technology Agency Exploratory Research , Advanced Technology , Japan Society , Science World Premier Initiative ,

Scientists Use Computational Results to Create Innovative Drugs

Chemists frequently use computer simulations as a guide much like a compass helps an explorer efficiently reach a destination on their map to effectively work out the specifics of a basic reaction notion they have in mind. ....

Tsuyoshi Mita , Yu Harabuchi , Hiroki Hayashi , Alex Smith , Satoshi Maeda , Hitomi Katsuyama , Hideaki Takano , Scientific Research , Fugaku Trust For Medical Research , Technology Agency , Hokkaido University , Akiyama Life Science Foundation , World Premier International Research Initiative , Exploratory Research For Advanced Technology , Ube Industries Foundation , Naito Foundation , Japan Society For The Promotion Of Science , Challenging Research Exploratory , Institute For Chemical Reaction Design , Uehara Memorial Foundation , Ministry Of Education , Use Computational Results , Create Innovative , Study Lead Author , Japan Science , Exploratory Research ,

Method Enables Recycling of CO2 and Drug Development Simultaneously

Researchers at the Institute for Chemical Reaction Design and Discovery (ICReDD) in Hokkaido University have formulated a technique that has the potential to assist in the recycling of waste carbon dioxide (CO2) while also creating molecules beneficial for drug development. ....

Tsuyoshi Mita , Technology Agency Exploratory Research For Advanced , Fugaku Trust For Medical Research , Drug Development , Hokkaido University , Naito Foundation , Challenging Research Exploratory , Uehara Memorial Foundation , Institute For Chemical Reaction Design , Chemical Reaction Design , Method Enables Recycling , Professor Tsuyoshi Mita , Yong You , Study First Author , Japan Science , Technology Agency , Exploratory Research , Advanced Technology , Japan Society , Challenging Research , Fugaku Trust , Medical Research ,

Heart Tissue in a Dish Reveals New Links Between Neurodegeneration and Heart Disease

/PRNewswire/ One of the leading reasons why children and adults need heart transplants is a condition called dilated cardiomyopathy (DCM). Some cases of. ....

United States , University Of Cincinnati , University Of California San Francisco , University Of California San Diego , Alessandro Bertero , Bruce Conklin , Yuichiro Miyaoka , Charles Murry , Nathan Salomonis , Aidan Fenix , Mochida Memorial Foundation , Department Of Cellular , National Institute Of Diabetes , Nature Communications , National Science Foundation , Armenise Harvard Laboratory , Tokyo Metropolitan Institute Of Medical Science , University Of Washington , Naito Foundation , Blood Institute , Uehara Memorial Foundation , International Fellowship , National Heart , Research Foundation , University Of Turin , University Of Cincinnati Department Electrical Engineering ,

Superoxide produced in the cochlea of inner ears causes acquired hearing loss

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IMAGE: The top image is a cross-section of the organ of Corti from a 12-month-old mouse (homozygous Nox3-Cre+/+;tdTomato) and the bottom image is an illustration of this. Red fluorescent proteins (tdTomato),.
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Credit: Takehiko Ueyama
Professor UEYAMA Takehiko (Biosignal Research Center, Kobe University) and the inner ear research group (Kyoto Prefectural University of Medicine) have identified the cell types in the inner ear cochlea (
1) responsible for the production of superoxide (Nox3
2-expressing cells). They achieved this by using genetically modified mice that they developed. The researchers discovered that these superoxide-producing cells increase in number in response to aging, noise damage, and ototoxic drugs, thus causing age-related, noise-induced and drug-induced hearing loss. In addition, they were able to suppress the onset of these three types of acquired hearing loss in genetically modified mice with no Nox3 exp ....

Shigeru Hirano , Yuzuru Ninoyu , Hirofumi Sakaguchi , Hiroaki Mohri , Naoaki Saito , Takehiko Ueyama , Alfonso Corti , Japan Foundation For Applied Enzymology , Technology Association , Research Methodology , World Health Organization , Terumo Life Science Foundation , Takehiko Biosignal Research Center , Kobe University , Society For Neuroscience Journal Of On , Kyoto Prefectural University Of Medicine , Naito Foundation , Research Background , Japan Society For The Promotion Of Science , Uehara Memorial Foundation , Biosignal Research Center , Kyoto Prefectural University , Hyogo Science , Japan Foundation , Applied Enzymology , Terumo Life Science ,